Brigimadlin
Product Specifications
CAS Number
2095116-40-6
Target
MDM-2/p53, E1/E2/E3 Enzyme, Mdm2, p53
Related Pathways
Ubiquitination, Apoptosis
Purity
0.9817
Bioactivity
Brigimadlin (BI 907828) is an orally active and highly potent E3 ubiquitin-protein ligase MDM2-p53 antagonist with antitumor activity.Brigimadlin can be used to study metastatic BTC, PDAC, lung adenocarcinoma, or bladder cancer.
Smiles
C(N1[C@@]2([C@H]([C@]3([C@@]1(CC=4N3N=C5C4C=CC(C(O)=O)=C5C)[H])[H])C6=C(F)C(Cl)=CC=C6)C=7C(NC2=O)=CC(Cl)=CC7)C8CC8
Molecular Formula
C31H25Cl2FN4O3
Molecular Weight
591.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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