SHR0687
Product Specifications
CAS Number
2168573-03-1
Target
Others
Related Pathways
Others
Bioactivity
SHR0687 is a Highly Potent KOR Agonist. SHR0687 showed excellent selectivity over other opioid receptors, such as MOR and DOR. In addition, SHR0687 displayed favorable PK profiles across species, as well as robust in vivo efficacy in a rat carrageenan-induced pain model. Notably, SHR0687 exhibited negligible blood−brain barrier penetration, which was meaningful in minimizing CNS-related side effects.
Smiles
C([C@H](NC([C@H](NC([C@@H](CC1=CC=CC=C1)NC(CNC[C@H](C)C2=CC=CC=C2)=O)=O)CC(C)C)=O)CCCCN)(=O)N3CCC(NC(NC)=O)CC3
Molecular Formula
C39H60N8O5
Molecular Weight
720.94
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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