VTP50469 mesylate

Product Specifications

CAS Number

2169919-27-9

Target

Apoptosis, Epigenetic Reader Domain, Others

Related Pathways

Chromatin/Epigenetic, Apoptosis, Others

Bioactivity

VTP-50469 is a novel, potent, selective, orally-available MeninMLL1 inhibitor, being effectively against MLL-rearranged and NPM1c+ leukemia, selectively killing cell lines with MLLrearrangements and NPM1c+ mutations.

Smiles

CS(O)(=O)=O.CS(O)(=O)=O.CC(C)N(C(C)C)C(=O)c1cc(F)ccc1Oc1cncnc1N1CC2(C1)CCN(C[C@H]1CC[C@@H](CC1)NS(C)(=O)=O)CC2

Molecular Formula

C33H51FN6O7S2

Molecular Weight

726.9244

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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