VTP50469 mesylate
Product Specifications
CAS Number
2169919-27-9
Target
Apoptosis|||Epigenetic Reader Domain|||Others
Related Pathways
Chromatin/Epigenetic|||Apoptosis|||Others
Bioactivity
VTP-50469 is a novel, potent, selective, orally-available MeninMLL1 inhibitor, being effectively against MLL-rearranged and NPM1c+ leukemia, selectively killing cell lines with MLLrearrangements and NPM1c+ mutations.
Smiles
CS(O)(=O)=O.CS(O)(=O)=O.CC(C)N(C(C)C)C(=O)c1cc(F)ccc1Oc1cncnc1N1CC2(C1)CCN(C[C@H]1CC[C@@H](CC1)NS(C)(=O)=O)CC2
Molecular Formula
C33H51FN6O7S2
Molecular Weight
726.9244
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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