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RK-582

Product Specifications

CAS Number

2171388-28-4

Target

PARP, Others

Related Pathways

Chromatin/Epigenetic, Others, DNA Damage/DNA Repair

Bioactivity

RK-582 is an orally efficacious spiroindolinone-based tankyrase inhibitor for the treatment of colon cancer. It exhibits a markedly improved robust tumor growth inhibition in a COLO-320DM mouse xenograft model when orally administered.

Smiles

O=C1C2(C=3C(N1C)=CC(=CC3F)N4C[C@@H](C)O[C@@H](C)C4)CCN(CC2)C=5NC6=C(C(=O)N5)CCCN6C

Molecular Formula

C27H35FN6O3

Molecular Weight

510.6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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