Tivumecirnon
Product Specifications
CAS Number
2174938-78-2
Target
CCR
Related Pathways
GPCR/G Protein, Immunology/Inflammation, Microbiology/Virology
Purity
0.9988
Bioactivity
Tivumecirnon (FLX475) is a selective and orally active CCR4 antagonist that inhibits the infiltration and migration of regulatory T cells (Tregs) into the tumour microenvironment, exhibiting antitumour activity.
Smiles
[C@H](C)(N1C=2C(C(C(F)(F)F)=N1)=NC=C(N2)N3CC(C3)[C@@H]4CN(CCO)CCC4)C5=C(Cl)C=C(Cl)C=C5
Molecular Formula
C24H27Cl2F3N6O
Molecular Weight
543.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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