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GSK3527497 HCl

Product Specifications

CAS Number

2215855-51-7

Target

Others

Related Pathways

Others

Bioactivity

GSK3527497 is a potent and selective inhibitor of Transient Receptor Potential Vanilloid‐4 (TRPV4) with IC50 = 12 nM) for the treatment of heart failure and respiratory diseases. GSK3527497 is a preclinical candidate suitable for oral and iv administration that is projected to inhibit TRPV4 effectively in patients from a low daily clinical dose.

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Cl.NC[C@]1(O)CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cn1

Molecular Formula

C17H17Cl2FN4O4S

Molecular Weight

463.3054

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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