GSK3527497 HCl
Product Specifications
CAS Number
2215855-51-7
Target
Others
Related Pathways
Others
Bioactivity
GSK3527497 is a potent and selective inhibitor of Transient Receptor Potential Vanilloid?4 (TRPV4) with IC50 = 12 nM) for the treatment of heart failure and respiratory diseases. GSK3527497 is a preclinical candidate suitable for oral and iv administration that is projected to inhibit TRPV4 effectively in patients from a low daily clinical dose.
Smiles
Cl.NC[C@]1(O)CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cn1
Molecular Formula
C17H17Cl2FN4O4S
Molecular Weight
463.3054
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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