MEDS433
Product Specifications
CAS Number
2241027-61-0
Target
Others, Dehydrogenase
Related Pathways
Others, Metabolism
Bioactivity
MEDS433 is a dihydroorotate dehydrogenase inhibitor (IC50 1.2 nM) . MEDS433 inhibited the in vitro replication of hCoV-OC43 and hCoV-229E, as well as of SARS-CoV-2, at low nanomolar range. Notably, the anti-SARS-CoV-2 activity of MEDS433 against SARS-CoV-2 was also observed in kidney organoids generated from human embryonic stem cells.
Smiles
C(NC1=C(F)C(F)=C(C(F)=C1F)C2=CC=CC=C2)(=O)C3=C4N(NC3=O)C=CC=C4
Molecular Formula
C20H11F4N3O2
Molecular Weight
401.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
A08433-1-iFluor647 100 µg
Anti-LARP4B Antibody Picoband®, iFluor647 Conjugate
Sign In for Pricing
View Details 
