MEDS433
Product Specifications
Target
Others|||Dehydrogenase
Related Pathways
Others|||Metabolism
Bioactivity
MEDS433 is a dihydroorotate dehydrogenase inhibitor (IC50 1.2 nM) . MEDS433 inhibited the in vitro replication of hCoV-OC43 and hCoV-229E, as well as of SARS-CoV-2, at low nanomolar range. Notably, the anti-SARS-CoV-2 activity of MEDS433 against SARS-CoV-2 was also observed in kidney organoids generated from human embryonic stem cells.
Smiles
C(NC1=C(F)C(F)=C(C(F)=C1F)C2=CC=CC=C2)(=O)C3=C4N(NC3=O)C=CC=C4
Molecular Formula
C20H11F4N3O2
Molecular Weight
401.31
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/7870DD8E-92D7-494F-BD32-918F4BA571E4/T69743
CAS Number
2241027-61-0
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6398867-01 0.1 mL
YBX2 (Y-box-binding Protein 2, Contrin, CSDA3, DNA-binding Protein C, Dbpc, Germ Cell-specific Y-box-binding Protein, MSY2, MSY2 Homolog) (Biotin)
Ask
View Details 
MBS6398867-02 5x 0.1 mL
YBX2 (Y-box-binding Protein 2, Contrin, CSDA3, DNA-binding Protein C, Dbpc, Germ Cell-specific Y-box-binding Protein, MSY2, MSY2 Homolog) (Biotin)
Ask
View Details 