AMG-315
Product Specifications
CAS Number
2244425-65-6
Target
Others
Related Pathways
Others
Bioactivity
AMG-315 is a Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes. AMG-315 is a chiral arachidonoyl ethanolamide (AEA) analogue or (13S,1′R) -dimethylanandamide. AMG-315 is a high affinity ligand for the CB1 receptor (Ki of 7.8 ± 1.4 nM) that behaves as a potent CB1 agonist in vitro (EC50 = 0.6 ± 0.2 nM) . AMG-315 is the first potent AEA analogue with significant stability for all endocannabinoid hydrolyzing enzymes as well as the oxidative enzymes COX-2. AMG-315 will serve as a very useful endocannabinoid probe.
Smiles
C(CC/C=C\C/C=C\C/C=C\[C@H](/C=C\CCCCC)C)C(N[C@@H](CO)C)=O
Molecular Formula
C24H41NO2
Molecular Weight
375.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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