TSI-13-57
Product Specifications
CAS Number
2257427-45-3
Target
MyD88, TNF
Related Pathways
Immunology/Inflammation, Apoptosis
Purity
0.9963
Bioactivity
TSI-13-57 is a MyD88 inhibitor or pan-TLR inhibitor that suppresses MyD88 TIR domain dimerization without affecting MyD88-receptor interactions. TSI-13-57 inhibits LPS-induced TNF-α (IC50 = 6.73 mM) .
Smiles
OC1=CC=C(C=2N(N=C(C2)C3=CC=C(OCCN4CCCCC4)C=C3)C5=CC=C(O)C=C5)C=C1
Molecular Formula
C28H29N3O3
Molecular Weight
455.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6308839-01 0.2 mL
HTR3A, NT (HTR3A, 5HT3R, HTR3, 5-hydroxytryptamine receptor 3A, 5-hydroxytryptamine receptor 3, Serotonin receptor 3A, Serotonin-gated ion channel receptor) (Biotin)
Sign In for Pricing
View Details MBS6308839-02 5x 0.2 mL
HTR3A, NT (HTR3A, 5HT3R, HTR3, 5-hydroxytryptamine receptor 3A, 5-hydroxytryptamine receptor 3, Serotonin receptor 3A, Serotonin-gated ion channel receptor) (Biotin)
Sign In for Pricing
View Details MBS730803-01 48 Well
Mouse Macrophage MigRation Inhibitory Factor ELISA Kit
Sign In for Pricing
View Details MBS730803-02 96 Well
Mouse Macrophage MigRation Inhibitory Factor ELISA Kit
Sign In for Pricing
View Details