TSI-13-57
Product Specifications
CAS Number
2257427-45-3
Target
MyD88|||TNF
Related Pathways
Immunology/Inflammation|||Apoptosis
Purity
0.9963
Bioactivity
TSI-13-57 is a MyD88 inhibitor or pan-TLR inhibitor that suppresses MyD88 TIR domain dimerization without affecting MyD88-receptor interactions. TSI-13-57 inhibits LPS-induced TNF-? (IC50 = 6.73 mM) .
Smiles
OC1=CC=C(C=2N(N=C(C2)C3=CC=C(OCCN4CCCCC4)C=C3)C5=CC=C(O)C=C5)C=C1
Molecular Formula
C28H29N3O3
Molecular Weight
455.55
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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