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TSI-13-57

Product Specifications

CAS Number

2257427-45-3

Target

MyD88|||TNF

Related Pathways

Immunology/Inflammation|||Apoptosis

Purity

0.9963

Bioactivity

TSI-13-57 is a MyD88 inhibitor or pan-TLR inhibitor that suppresses MyD88 TIR domain dimerization without affecting MyD88-receptor interactions. TSI-13-57 inhibits LPS-induced TNF-? (IC50 = 6.73 mM) .

Smiles

OC1=CC=C(C=2N(N=C(C2)C3=CC=C(OCCN4CCCCC4)C=C3)C5=CC=C(O)C=C5)C=C1

Molecular Formula

C28H29N3O3

Molecular Weight

455.55

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/31B9D192-97B7-4901-BCBC-719FF3E1EE1D/T69719

Available Sizes

Curated Selection

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