TSI-13-57

Product Specifications

CAS Number

2257427-45-3

Target

MyD88|||TNF

Related Pathways

Immunology/Inflammation|||Apoptosis

Purity

0.9963

Bioactivity

TSI-13-57 is a MyD88 inhibitor or pan-TLR inhibitor that suppresses MyD88 TIR domain dimerization without affecting MyD88-receptor interactions. TSI-13-57 inhibits LPS-induced TNF-? (IC50 = 6.73 mM) .

Smiles

OC1=CC=C(C=2N(N=C(C2)C3=CC=C(OCCN4CCCCC4)C=C3)C5=CC=C(O)C=C5)C=C1

Molecular Formula

C28H29N3O3

Molecular Weight

455.55

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

E56G3557 100 µL

Phospho-Tau Rabbit Monoclonal Antibody

Ask

View Details

NBP3-06879MFV500 0.1 mL

Mouse Monoclonal Mono- and polyubiquitinylated conjugates Antibody (UBCJ2) [mFluor Violet 500 SE]

Ask

View Details

MPX4215K Each

Magic™ Membrane Protein Human NPR1 (Natriuretic peptide receptor 1) Expressed in Yeast with 6xHis tag at the N-terminus for Antibody Discovery, PaRoom Temperatureial (33-473aa)

Ask

View Details

43374061 1.0 µg DNA

SENP5 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

Ask

View Details

MBS9905326 Inquire

Duck UPF0565 Protein C2orf69 (C2ORF69) ELISA Kit

Ask

View Details

GA209878 1 Kit

Mouse 4933402J15Rik activation kit by CRISPRa

Ask

View Details