Relutrigine
Product Specifications
CAS Number
2392951-29-8
Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9968
Bioactivity
Relutrigine (PRAX-562) is an orally active, long-acting sodium current inhibitor that preferentially suppresses sustained INa induced by TX-II or SCN8A N1768D mutations (IC50=141/75 nM) . It reduces neuronal intrinsic excitability and may be used for anticonvulsant therapy.
Smiles
C(OCC)(F)(F)C=1N2C(=NN1)C=NC(=C2)C=3C=C(F)C(OCC(F)(F)F)=NC3
Molecular Formula
C15H11F6N5O2
Molecular Weight
407.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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