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Relutrigine

Product Specifications

CAS Number

2392951-29-8

Target

Sodium Channel

Related Pathways

Membrane transporter/Ion channel

Purity

0.9968

Bioactivity

Relutrigine (PRAX-562) is an orally active, long-acting sodium current inhibitor that preferentially suppresses sustained INa induced by TX-II or SCN8A N1768D mutations (IC50=141/75 nM) . It reduces neuronal intrinsic excitability and may be used for anticonvulsant therapy.

Smiles

C(OCC)(F)(F)C=1N2C(=NN1)C=NC(=C2)C=3C=C(F)C(OCC(F)(F)F)=NC3

Molecular Formula

C15H11F6N5O2

Molecular Weight

407.27

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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