What is the catalog number for M‐89 MLL inhibitor?

The catalog number for M‐89 MLL inhibitor is T69629.

What sizes are available for M‐89 MLL inhibitor?

M‐89 MLL inhibitor is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does M‐89 MLL inhibitor come in?

M‐89 MLL inhibitor is available in 3 different pack sizes.

Is M‐89 MLL inhibitor in stock?

M‐89 MLL inhibitor is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures M‐89 MLL inhibitor?

M‐89 MLL inhibitor is manufactured by Molfinity.

What is the estimated delivery time for M‐89 MLL inhibitor?

Estimated delivery time for M‐89 MLL inhibitor is approximately 10 business day(s), depending on your location.

M‐89 MLL inhibitor

Product Specifications

CAS Number

2446155-01-5

Target

Others

Related Pathways

Others

Bioactivity

M‐89 is a Highly Potent Inhibitor of the Menin-Mixed Lineage Leukemia (Menin-MLL) Protein−Protein Interaction (Kd = 1.4 nM; IC50 = 25nM) . M-89 binds to menin with a Kd value of 1.4 nM and effectively engages cellular menin protein at low nanomolar concentrations. M-89 inhibits cell growth in the MV4;11 and MOLM-13 leukemia cell lines carrying MLL fusion with IC50 values of 25 and 55 nM, respectively, and demonstrates >100-fold selectivity over the HL-60 leukemia cell line lacking MLL fusion.