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Dapivirine HCl

Product Specifications

CAS Number

244768-47-6

Target

Apoptosis, HIV Protease, Autophagy, Reverse Transcriptase, Others

Related Pathways

Autophagy, Proteases/Proteasome, Others, Apoptosis, Microbiology/Virology

Bioactivity

Dapivirine HCl is the salt form of Dapivirine, also known as TMC120, a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. The HIV-1 replication inhibitor dapivirine (DPV) is one of the most promising drug candidates being used in topical microbicide products for prevention of HIV-1 sexual transmission.

Smiles

N(C1=C(C)C=C(C)C=C1C)C2=NC(NC3=CC=C(C#N)C=C3)=NC=C2.Cl

Molecular Formula

C20H20ClN5

Molecular Weight

365.86

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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