Dapivirine HCl
Product Specifications
CAS Number
244768-47-6
Target
Apoptosis, HIV Protease, Autophagy, Reverse Transcriptase, Others
Related Pathways
Autophagy, Proteases/Proteasome, Others, Apoptosis, Microbiology/Virology
Bioactivity
Dapivirine HCl is the salt form of Dapivirine, also known as TMC120, a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. The HIV-1 replication inhibitor dapivirine (DPV) is one of the most promising drug candidates being used in topical microbicide products for prevention of HIV-1 sexual transmission.
Smiles
N(C1=C(C)C=C(C)C=C1C)C2=NC(NC3=CC=C(C#N)C=C3)=NC=C2.Cl
Molecular Formula
C20H20ClN5
Molecular Weight
365.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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