AWD12-281 sodium
Product Specifications
CAS Number
247584-21-0
Target
Others
Related Pathways
Others
Bioactivity
AWD 12-281 is a selective phosphodiesterase 4 (PDE4) inhibitor for the treatment of lung inflammation using inhalative administration. AWD 12-281 Is Active in a New Guinea-Pig Model of Allergic Skin Inflammation Predictive of Human Skin Penetration and Suppresses Both Th1 and Th2 Cytokines in Mice. AWD 12-281 is a very promising drug candidate not only for the treatment of lung inflammation using inhalative administration but also for the treatment of atopic dermatitis.
Smiles
ClC1=CN=CC(Cl)=C1NC(C(C(C2=C3)=CN(CC4=CC=C(C=C4)F)C2=CC=C3[O-])=O)=O.[Na+]
Molecular Formula
C22H13Cl2FN3NaO3
Molecular Weight
480.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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