TG11-77 HCl
Product Specifications
CAS Number
2490544-34-6
Target
Others
Related Pathways
Others
Bioactivity
TG11-77 HCl is a novel, Potent, Selective, Water Soluble, Brain-Permeable EP2 Receptor Antagonist. TG11-77 HCl has a Schild KB of 9.7 nM on EP2, a water solubility of 2.5 mM, a brain-to-plasma ratio of 0.4, and a plasma half-life of 2.4 h in mice. TG11-77 HCl are representative second generation EP2 antagonists with improved pharmacodynamic and pharmacokinetic properties.
Smiles
C(CNC(=O)C=1C=NC(NC2=CC(C)=CC(C)=N2)=NC1)C=3C=4C(NC3C)=CC=CC4.Cl
Molecular Formula
C23H24N6O.xHCl
Molecular Weight
436.944
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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