MMT5-14
Product Specifications
CAS Number
2719679-31-7
Target
Others, SARS-CoV
Related Pathways
Others, Microbiology/Virology
Bioactivity
MMT5-14 is a SARS-CoV-2 inhibitor. MMT5-14 showed 2- to 7-fold higher antiviral activity in four variants of SARS-CoV-2. By reducing premature hydrolysis in hamsters, MMT5-14 increased the prodrug concentration by 200- to 300-fold in the plasma and lungs but also enhanced lung accumulation of the active metabolite triphosphate nucleosides (NTP) by 5-fold.
Smiles
C(#N)[C@]1(O[C@H](COP(OC2=CC=CC=C2)(N[C@H](C(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)C)=O)[C@@H](O)[C@H]1O)C=3N4C(=CC3)C(N)=NC=N4
Molecular Formula
C39H55N6O8P
Molecular Weight
766.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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