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MMT5-14

Product Specifications

CAS Number

2719679-31-7

Target

Others|||SARS-CoV

Related Pathways

Others|||Microbiology/Virology

Bioactivity

MMT5-14 is a SARS-CoV-2 inhibitor. MMT5-14 showed 2- to 7-fold higher antiviral activity in four variants of SARS-CoV-2. By reducing premature hydrolysis in hamsters, MMT5-14 increased the prodrug concentration by 200- to 300-fold in the plasma and lungs but also enhanced lung accumulation of the active metabolite triphosphate nucleosides (NTP) by 5-fold.

Smiles

C(#N)[C@]1(O[C@H](COP(OC2=CC=CC=C2)(N[C@H](C(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)C)=O)[C@@H](O)[C@H]1O)C=3N4C(=CC3)C(N)=NC=N4

Molecular Formula

C39H55N6O8P

Molecular Weight

766.86

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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