Berubicin HCl
Product Specifications
CAS Number
293736-67-1
Target
Apoptosis, Caspase, NF-κB, Others
Related Pathways
Apoptosis, Others, Proteases/Proteasome, NF-κB
Bioactivity
Berubicin hydrochloride is the hydrochloride salt of the anthracycline derivative berubicin with potential antineoplastic activity. Berubicin intercalates into DNA and interrupts topoisomerase II activity, resulting in the inhibition of DNA replication and repair, and RNA and protein synthesis. Unlike other anthracycline derivatives, this agent crosses the blood-brain barrier (BBB) .
Smiles
OC=1C2=C([C@@H](O[C@H]3C[C@H](N)[C@H](OCC4=CC=CC=C4)[C@H](C)O3)C[C@@](C(CO)=O)(O)C2)C(O)=C5C1C(=O)C=6C(C5=O)=C(OC)C=CC6.Cl
Molecular Formula
C34H36ClNO11
Molecular Weight
670.1
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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