YM-202074
Product Specifications
CAS Number
299900-83-7
Target
Others, GluR
Related Pathways
Others, Neuroscience
Bioactivity
YM-202074 is a high affinity, selective metabotropic glutamate receptor type 1 (mGlu1) antagonist. YM-202074 binds an allosteric site of the rat mGlu1 receptor with a Ki of 4.8 nM. It inhibits mGlu1-mediated inositol phosphates production (IC50 = 8.6 nM in rat cerebellar granule cells) .
Smiles
C(N(C)C1CCCCC1)(=O)C2=CN3C=4C(N=C3S2)=CC=C(CN(CCOC)C)C4
Molecular Formula
C22H30N4O2S
Molecular Weight
414.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
E1722Ra-01 48 Well
Rat A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAMTS4 ELISA KIT
Sign In for Pricing
View Details E1722Ra-02 96 Well
Rat A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAMTS4 ELISA KIT
Sign In for Pricing
View Details E1722Ra-03 5x 96 Tests
Rat A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAMTS4 ELISA KIT
Sign In for Pricing
View Details E1722Ra-04 10x 96 Tests
Rat A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAMTS4 ELISA KIT
Sign In for Pricing
View Details 
