YM-202074
Product Specifications
CAS Number
299900-83-7
Target
Others|||GluR
Related Pathways
Others|||Neuroscience
Bioactivity
YM-202074 is a high affinity, selective metabotropic glutamate receptor type 1 (mGlu1) antagonist. YM-202074 binds an allosteric site of the rat mGlu1 receptor with a Ki of 4.8 nM. It inhibits mGlu1-mediated inositol phosphates production (IC50 = 8.6 nM in rat cerebellar granule cells) .
Smiles
C(N(C)C1CCCCC1)(=O)C2=CN3C=4C(N=C3S2)=CC=C(CN(CCOC)C)C4
Molecular Formula
C22H30N4O2S
Molecular Weight
414.56
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6148942-01 0.1 mL
PNN (DRS, MEMA, Pinin, 140kD Nuclear and Cell Adhesion-related Phosphoprotein, Desmosome-associated Protein, Domain-rich Serine Protein, Melanoma Metastasis Clone A Protein, Nuclear Protein SDK3, SR-like Protein) (FITC)
Ask
View Details MBS6148942-02 5x 0.1 mL
PNN (DRS, MEMA, Pinin, 140kD Nuclear and Cell Adhesion-related Phosphoprotein, Desmosome-associated Protein, Domain-rich Serine Protein, Melanoma Metastasis Clone A Protein, Nuclear Protein SDK3, SR-like Protein) (FITC)
Ask
View Details MBS087450-01 48 Well
Porcine Purinergic Receptor P2Y, G Protein Coupled 1 ELISA Kit
Ask
View Details 
MBS087450-02 96 Well
Porcine Purinergic Receptor P2Y, G Protein Coupled 1 ELISA Kit
Ask
View Details MBS087450-03 5x 96 Well
Porcine Purinergic Receptor P2Y, G Protein Coupled 1 ELISA Kit
Ask
View Details