AG-13958 monohydrochloride
Product Specifications
CAS Number
319463-49-5
Target
Others, VEGFR
Related Pathways
Tyrosine Kinase/Adaptors, Others, Angiogenesis
Bioactivity
AG-13958 monohydrochloride is the HCl salt of AG-13958 --- a VEGFA inhibitor potentially for the treatment of age-related macular degeneration. Neovascular AMD, a subtype characterized by the growth of new, pathologic blood vessels, results in most of the cases of severe and rapid vision loss associated with AMD. A critical activator of angiogenesis in neovascular AMD is VEGF.
Smiles
C(=C/C1=CC=CC=N1)\C=2C=3C(=CC(NC4=CC(NC(=O)C=5N(C)N=C(C)C5)=C(F)C=C4)=CC3)NN2.Cl
Molecular Formula
C26H23ClFN7O
Molecular Weight
503.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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