CK0106023
Product Specifications
CAS Number
336115-72-1
Target
Others, Kinesin
Related Pathways
Others, Cytoskeletal Signaling
Bioactivity
CK0106023 was specific inhibitor of KSP. In tumor-bearing mice, CK0106023 exhibited antitumor activity comparable to or exceeding that of paclitaxel and caused the formation of monopolar mitotic figures identical to those produced in cultured cells. KSP was most abundant in proliferating human tissues and was absent from cultured postmitotic neurons.
Smiles
C(N(C(=O)C1=CC=C(Br)C=C1)CCCN(C)C)(CC)C=2N(CC3=CC=CC=C3)C(=O)C=4C(N2)=CC(Cl)=CC4
Molecular Formula
C30H32BrClN4O2
Molecular Weight
595.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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