PPI-2458
Product Specifications
Target
Others|||Aminopeptidase
Related Pathways
Others|||Metabolism
Bioactivity
PPI-2458 is a synthetic derivative of fumagillin with antineoplastic and cytotoxic properties. PPI-2458 irreversibly inhibits the enzyme methionine aminopeptidase type 2 (MetAP2), thereby preventing abnormal cell growth and angiogenesis. PPI-2458 is reported to have a better toxicity profile compared to other agents of its class.
Smiles
C[C@@]1([C@@]2([C@@]3(CO3)CC[C@@H](OC(N[C@H]([C@@H](C)C)C(N)=O)=O)[C@H]2OC)[H])[C@@H](CC=C(C)C)O1
Molecular Formula
C22H36N2O6
Molecular Weight
424.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/98F3C5A6-8FCD-4CD2-B2DA-CFBAA66F08D3/T69258
CAS Number
431077-35-9
Available Sizes
Curated Selection
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