Verrucarin J
Product Specifications
CAS Number
4643-58-7
Target
ROS|||Antifungal|||Reactive Oxygen Species|||Anti-infection|||Apoptosis|||Others|||Virus Protease|||Antibiotic
Related Pathways
Microbiology/Virology|||Apoptosis|||Immunology/Inflammation|||Metabolism|||NF-?B|||Others
Bioactivity
Verrucarin J (Muconomycin B), derived from the Myrothecium fungus family, effectively generates reactive oxygen species (ROS) to induce apoptosis in various cancer cell lines, including A549, HCT 116, and SW-620. Besides its anticancer properties, it exhibits antifungal activity against Candida albicans and Mucor miehei. Furthermore, it notably inhibits the arenavirus Junin (JUNV) yield with an IC 50 of 1.2 ng/mL.
Smiles
CC1=CC2OC3CC4OC(=O)\C=C/C=C/C(=O)OCC\C(C)=C\C(=O)OCC2(CC1)C4(C)C31CO1
Molecular Formula
C27H32O8
Molecular Weight
484.54
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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