GGTI-2166
Product Specifications
CAS Number
478908-51-9
Target
Others
Related Pathways
Others
Bioactivity
GGTI-2166 is a geranylgeranyl transferase I inhibitor. GGTI-2166 inhibit the pOC formation induced by RANKL or TNF-alpha in cultures of both mouse marrow-derived macrophage-colony-stimulating factor (M-CSF) dependent monocytes (MD cells) and the mouse monocyte cell line RAW 264.7 (RAW cells) . GGTI-2166 inhibited TRAP activity induced by RANKL or TNF-alpha in both cell cultures and prevented the incorporation of [3H]all-trans geranylgeraniol into prenylated proteins in RAW cells.
Smiles
C(N[C@H](C(OC)=O)CC(C)C)(=O)C1=C(C=C(NCC2=CN=CN2)C=C1)C3=C(C)C=CC=C3
Molecular Formula
C25H30N4O3
Molecular Weight
434.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1332985-01 0.02 mg (E-Coli)
Recombinant Chlamydophila abortus GTPase Der (der)
Sign In for Pricing
View Details MBS1332985-02 0.02 mg (Yeast)
Recombinant Chlamydophila abortus GTPase Der (der)
Sign In for Pricing
View Details MBS1332985-03 0.1 mg (E-Coli)
Recombinant Chlamydophila abortus GTPase Der (der)
Sign In for Pricing
View Details MBS1332985-04 0.1 mg (Yeast)
Recombinant Chlamydophila abortus GTPase Der (der)
Sign In for Pricing
View Details MBS1332985-05 0.02 mg (Baculovirus)
Recombinant Chlamydophila abortus GTPase Der (der)
Sign In for Pricing
View Details MBS1332985-06 0.02 mg (Mammalian-Cell)
Recombinant Chlamydophila abortus GTPase Der (der)
Sign In for Pricing
View Details