UC-857993
Product Specifications
CAS Number
487001-04-7
Target
Others, Ras, ERK
Related Pathways
MAPK, Others, GPCR/G Protein
Bioactivity
UC-857993, a selective SOS1-Ras inhibitor (Kd=14.7 μM, His6-SOS1cat), effectively suppresses catalytic activity. In addition to inhibiting ERK and Ras activation, it also hampers the growth of mouse embryonic fibroblasts (MEFs) .
Smiles
C(O)(=O)C=1C=C2C=3N(C(C4C2C=CC4)C5=C(Cl)C=CC=C5)CC6C(C3C1)C=CC6
Molecular Formula
C25H22ClNO2
Molecular Weight
403.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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