Clozapine HCl
Product Specifications
CAS Number
54241-01-9
Target
Others, Dopamine Receptor, 5-HT Receptor, AChR, Adrenergic Receptor
Related Pathways
Neuroscience, Others, GPCR/G Protein
Bioactivity
Clozapine HCl is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a major adverse effect associated with administration of this agent.
Smiles
Cl.CN1CCN(CC1)C1=NC2=C(NC3=C1C=CC=C3)C=CC(Cl)=C2
Molecular Formula
C18H20Cl2N4
Molecular Weight
363.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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