RXPA 380
Product Specifications
CAS Number
564479-79-4
Target
Others|||Angiotensin-converting Enzyme (ACE)
Related Pathways
Others|||Metabolism
Bioactivity
RXPA 380, a C-terminal specific angiotensin-converting enzyme (ACE) inhibitor, exhibits high affinity with a Ki of 3 nM. It effectively inhibits C-domain mutants of human recombinant ACE, demonstrating potent inhibition with an IC50 of 2.5 nM.
Smiles
P([C@H](CC1=CC=CC=C1)NC(OCC2=CC=CC=C2)=O)(=O)(O)C3C(C(N[C@@H](CC=4C=5C(NC4)=CC=CC5)C(O)=O)=O)CCC3
Molecular Formula
C33H36N3O7P
Molecular Weight
617.63
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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