Aculeacin A
Product Specifications
CAS Number
58814-86-1
Target
Others
Related Pathways
Others
Bioactivity
Aculeacin A is used to study mutations that lead to antibiotic resistance in Saccharomyces cerevisiae, the inhibition of Candida albicans and the morphogenetic transformation of Candida albicans when treated. Aculeacin A is a lipopeptide that inhibits ?-glucan synthesis in yeasts. The inhibition is due to the selective blockage of glucan synthase. Aculeacin A, an amphophilic antibiotic, inhibits the biosynthesis of ??glucan by selective blockage of ? (1?3) glucan synthase.
Smiles
O=C1N2C(C(O)C(C)C2)C(=O)NC(O)C(O)CC(NC(CCCCCCCCCCCCCCC)=O)C(=O)NC(C(C)O)C(=O)N3C(C(=O)NC(C(C(O)C4=CC=C(O)C=C4)O)C(=O)NC1C(C)O)CC(O)C3
Molecular Formula
C50H81N7O16
Molecular Weight
1036.22
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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