CJ-463
Product Specifications
CAS Number
600142-19-6
Target
PAI-1|||Others
Related Pathways
Others|||Metabolism
Bioactivity
CJ-463 is a potent ans selective uPA inhibitor. Treatment with CJ-463 resulted in a significant inhibition of primary tumor growth, with the highest efficacy seen in the 100 mg/kg group. Urokinase (uPA) plays a crucial role in carcinogenesis by facilitating tumor cell invasion and metastasis. CJ-463 may be a novel agent for treatment of lung cancer.
Smiles
C(NC([C@@H](NC([C@H](NS(CC1=CC=CC=C1)(=O)=O)CO)=O)CO)=O)C2=CC=C(C(=N)N)C=C2
Molecular Formula
C21H27N5O6S
Molecular Weight
477.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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