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Detorubicin HCl

Product Specifications

CAS Number

64291-45-8

Target

Others

Related Pathways

Others

Bioactivity

Detorubicin is a semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation. Detorubicin is less toxic than daunorubicin.

Smiles

Cl.CCOC(OCC)C(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](N)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Molecular Formula

C33H40ClNO14

Molecular Weight

710.126

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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