TP-110
Product Specifications
CAS Number
688737-95-3
Target
Others
Related Pathways
Others
Bioactivity
TP-110 is a new proteasome inhibitor, which shows potent growth inhibition in various tumor cell lines. Treatment with TP-110 for 24 h in vitro induced apoptosis in multiple myeloma cell line RPMI8226. TP-110 reduced the intrinsic inhibitor of apoptosis proteins (IAPs), cIAP-1 and XIAP, that suppress executioner caspases.
Smiles
C(C(N[C@@H](CC1=CC=C(OC)C=C1)C(N[C@H](C(NC(CC2=CC=C(OC)C=C2)C=O)=O)C(C)C)=O)=O)C=3C4=C(C=CC3)C=CC=C4
Molecular Formula
C37H41N3O6
Molecular Weight
623.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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