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TP-110

Product Specifications

CAS Number

688737-95-3

Target

Others

Related Pathways

Others

Bioactivity

TP-110 is a new proteasome inhibitor, which shows potent growth inhibition in various tumor cell lines. Treatment with TP-110 for 24 h in vitro induced apoptosis in multiple myeloma cell line RPMI8226. TP-110 reduced the intrinsic inhibitor of apoptosis proteins (IAPs), cIAP-1 and XIAP, that suppress executioner caspases.

Smiles

C(C(N[C@@H](CC1=CC=C(OC)C=C1)C(N[C@H](C(NC(CC2=CC=C(OC)C=C2)C=O)=O)C(C)C)=O)=O)C=3C4=C(C=CC3)C=CC=C4

Molecular Formula

C37H41N3O6

Molecular Weight

623.74

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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