Complestatin

Complestatin is a compound extracted from Streptomyces lavendulae mycelia; on acid hydrolysis yields D-4-hydroxyphenylglycine & D-3,5-dichloro-4-hydroxyphenylglycine & acidic chromophore; inhibits gp120-CD4 binding. It is isolated from the culture broth of Streptomyces and has anti-HIV-1 activity. It has a role as a metabolite, an antimicrobial agent and an anti-HIV-1 agent.

OC1=C2C=3C=C4C(=CC3)C(=CN4)CC(NC(C(=O)C5=CC(Cl)=C(O)C(Cl)=C5)=O)C(=O)NC(C(=O)NC6C(=C2)C=C1OC=7C=CC(=CC7)CC(C(NC(C(O)=O)C8=CC=C(O)C=C8)=O)N(C)C(=O)C(NC6=O)C9=CC(Cl)=C(O)C(Cl)=C9)C%10=CC(Cl)=C(O)C(Cl)=C%10