Zelpolib
Product Specifications
CAS Number
701932-26-5
Target
DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Purity
0.9879
Bioactivity
Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), thereby inhibiting DNA replication and DNA double-strand break homologous recombination repair. It exhibits antiproliferative activity in triple-negative breast cancer cell lines, pancreatic cancer cell lines, and platinum-resistant pancreatic cancer cell lines.
Smiles
O=C(OC)C=1C=C(SC1NC(=S)NNC(=O)CCC2=CC=C(O)C(O)=C2)C=3C=CC=CC3
Molecular Formula
C22H21N3O5S2
Molecular Weight
471.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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