ADS-J1

Product Specifications

CAS Number

70236-51-0

Target

Others

Related Pathways

Others

Bioactivity

ADS-J1 is an HIV-1 entry inhibitor that potently inhibits seminal amyloid fibrillization and block fibril-mediated enhancement of viral infection. Semen-derived amyloid fibrils, comprising SEVI (semen-derived enhancer of viral infection) fibrils and SEM1 fibrils, may remarkably enhance HIV-1 sexual transmission and are potential targets for the development of an effective microbicide.

Smiles

[Na+].[Na+].[Na+].[Na+].COc1cc(N=Nc2cc(cc3cc(cc(O)c23)S([O-])(=O)=O)S([O-])(=O)=O)c(C)cc1Nc1nc(Nc2ccccc2)nc(Nc2ccc3c(O)c(N=Nc4cc(ccc4OC)S([O-])(=O)=O)c(cc3c2)S([O-])(=O)=O)n1