SIB-1893
Product Specifications
CAS Number
7370-21-0
Target
Others
Related Pathways
Others
Bioactivity
SIB-1893 is a highly selective non-competitive antagonist for the metabotropic glutamate mGlu5 receptor subtype; displays an IC50 value of 0.3 μM at hmGlu5, compared with > 100 μM at hmGlu1b, hmGlu2, hmGlu6, hmGlu7 and hmGlu8. It positive allosteric modulator at mGlu4 receptors.
Smiles
C(=C/C1=CC=CC=C1)\C=2N=C(C)C=CC2
Molecular Formula
C14H13N
Molecular Weight
195.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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