Luminespib mesylate
Product Specifications
CAS Number
747412-64-2
Target
Others
Related Pathways
Others
Bioactivity
Luminespib, also known as AUY-922, NVP-AUY922, VER52296, is a derivative of 4,5-diarylisoxazole and a third-generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins; the inhibition of cell proliferation; and the elevation of heat shock protein 72 (Hsp72) in a wide range of human tumor cell lines.
Smiles
C(NCC)(=O)C=1C(=C(ON1)C2=CC(C(C)(C)C)=C(O)C=C2O)C3=CC=C(CN4CCOCC4)C=C3
Molecular Formula
C27H33N3O5
Molecular Weight
479.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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