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UNC10112785

Product Specifications

CAS Number

748142-06-5

Target

Others

Related Pathways

Others

Bioactivity

UNC10112785 is a novel potent inhibitor of CDK8, CDK19, and CDK9 with IC50 at 1.05, 2.67, and 19.9 nM, respectively, causing MYC loss through both transcriptional and posttranslational mechanisms, and suppressing PDAC anchorage-dependent and anchorage-independent growth, inducing the substantial loss of MYC protein in both two-dimensional (2D) and 3D cell cultures.

Smiles

N(C=1N=C(C2=C3N(N=C2)N=CC=C3)C=CN1)C4=CC=C(C(C)C)C=C4

Molecular Formula

C19H18N6

Molecular Weight

330.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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