Amsacrine gluconate
Product Specifications
CAS Number
80277-07-2
Target
Others, Autophagy, Topoisomerase
Related Pathways
Others, DNA Damage/DNA Repair, Autophagy
Bioactivity
Amsacrine gluconate is an aminoacridine derivative with potential antineoplastic activity. Although its mechanism of action is incompletely defined, amsacrine may intercalate into DNA and inhibit topoisomerase II, resulting in DNA double-strand breaks, arrest of the S/G2 phase of the cell cycle, and cell death.
Smiles
OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.COc1cc(NS(C)(=O)=O)ccc1Nc1c2ccccc2nc2ccccc12
Molecular Formula
C27H31N3O10S
Molecular Weight
589.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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