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Amsacrine gluconate

Product Specifications

CAS Number

80277-07-2

Target

Others, Autophagy, Topoisomerase

Related Pathways

Others, DNA Damage/DNA Repair, Autophagy

Bioactivity

Amsacrine gluconate is an aminoacridine derivative with potential antineoplastic activity. Although its mechanism of action is incompletely defined, amsacrine may intercalate into DNA and inhibit topoisomerase II, resulting in DNA double-strand breaks, arrest of the S/G2 phase of the cell cycle, and cell death.

Smiles

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.COc1cc(NS(C)(=O)=O)ccc1Nc1c2ccccc2nc2ccccc12

Molecular Formula

C27H31N3O10S

Molecular Weight

589.62

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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