Totrombopag choline
Product Specifications
CAS Number
851606-62-7
Target
Others, Thrombopoietin Receptor
Related Pathways
Immunology/Inflammation, Others
Bioactivity
Totrombopag, also known LGD-4665, GSK2285921 and SB559448, is an oral thromobopoietin receptor agonist, is being developed as a new generation small molecule thrombopoietin (TPO) mimetic. It is a highly selective and potent agonist of the TPO receptor and therefore induces differentiation and proliferation of megakaryocytes. The pharmacologic characteristics indicate potential therapeutic use in thrombocytopenic patients with a variety of clinical etiologies.
Smiles
C[N+](C)(C)CCO.CC1=NN(C(=O)C1N=Nc1cccc(-c2cccc(c2)-c2nnn[n-]2)c1O)c1ccc(C)c(C)c1
Molecular Formula
C30H35N9O3
Molecular Weight
569.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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