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Blapsin B

Product Specifications

CAS Number

861145-00-8

Target

Others

Related Pathways

Others

Bioactivity

Blapsin B is a potent 14-3-3 inhibitor. Blapsin B is a naturally occurring compound isolated from the ethanol extract of the stink beetle, Blaps japanensis. Blapsin B potently inhibited 14-3-3 protein-protein interactions (PPIs) with IC (50) value of 10.0 ?M as determined by an ELISA assay, and 2.5 ?M in an FP assay, respectively. Blapsin B represent the first example of natural small-molecule 14-3-3 inhibitors.

Smiles

OC=1C=C2C(OCCC2=CC1O)C3=CC(O)=C(O)C=C3

Molecular Formula

C15H14O5

Molecular Weight

274.27

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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